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This quarterly publication alerts health professionals to potential signals detected through the review of case reports submitted to Health Canada. It is a useful mechanism to stimulate adverse reaction reporting as well as to disseminate information on suspected adverse reactions to health products occurring in humans before comprehensive risk-benefit evaluations and regulatory decisions are undertaken. >>>

The risks of smoking have been recognized by actors in the health field for many years: smoking is an important risk factor for the health of both smokers and non-smokers, because tobacco smoke contains more than 4,000 chemicals, of which at least 50 cause or are conducive to cancer. >>>

Although initially considered a chronic bacterial infection, CRS is now recognized as having multiple distinct components (eg, infection, inflammation), which have led to changes in therapeutic approaches (eg, increased use of corticosteroids). The role of bacteria in the persistence of chronic infections, and the roles of surgical and medical management are evolving. >>>